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The Law Office of 
Paul Hogan, LLC 
928 S. Broadway Wichita, KS 67211
Tel: 1(800) 426-6129
Fax: (316) 265-7568
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The Law Office of Paul Hogan, LLC
FAQs
Celebrex FAQs

What is Celebrex?

How does Celebrex work?

What are some possible side effects of Celebrex?

Who should NOT take Celebrex?

Does Celebrex increase the risk of experiencing major heart problems?

What is Celebrex? 
Celebrex is a non-steroidal anti-inflammatory drug (NSAID), manufactured by Pfizer, that is used to reduce pain and inflammation (swelling and soreness). It can be used to treat the following:

  • Osteoarthritis
  • Rhuematoid Arthritis
  • Acute Pain
  • Menstrual Pain
  • To reduce the number of colon and rectum growths (polyps) in patients with a disease called Familial Adenomatous Polyposis (FAP)
  • Shown to reduce cancer that happens with FAP

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How does Celebrex work? 
Celebrex works by inhibiting cyclooxygenase (Cox-2) enzymes that catalyze the production of prostanoids, substances that spur inflammation and pain in the body. Celebrex is believed to halt the production of prostanoids resulting in less pain, without compromising the homeostatic quality of cyclooxygenase in the kidneys, stomach, and gastrointestinal tract, protecting the GI system.

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What are some possible side effects of Celebrex? 
Side effects of the drug include:

  • headache 
  • indigestion 
  • upper respiratory tract infection 
  • diarrhea 
  • sinus inflammation 
  • stomach pain 
  • nausea
  • stomach ulcers
  • breathing problems
  • serious allergic skin reactiosn
  • swelling of face, lips, tongue, throat
  • serious kidney problems
  • liver damage

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Who should NOT take Celebrex? 
Do not take Celebrex if you:

  • have had an allergic-type reaction to sulfa medicines 
  • have had asthma, hives or allergic-type reactions after taking aspirin or other NSAID medicines 
  • are allergic to Celebrex or to any of the ingredients in Celebrex 
  • if you have asthma, you may have aspirin-sensitive asthma. If an aspirin-sensitive asthmatic takes aspirin it can cause severe narrowing of the airway (bronchospasm), and even death. Since this type of reaction to aspirin and other NSAID medicines have happened in aspirin-sensitive patients, aspirin-sensitive patients should not take Celebrex.

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Does Celebrex increase the risk of experiencing major heart problems? 
A recent study by the National Cancer Institute revealed that patients taking 400 milligrams of Celebrex per day were found to have a risk of experiencing heart problems that was 2.5 times greater than people not taking Celebrex. This same study found patients taking 800 milligrams of Celebrex experienced 3.4 times the risk of experiencing major heart problems.

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More About Celebrex

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